593836 A vial adapter element (10) for use in a drug mixing system comprising: a body (17)； a vial connection port (12) extending from the body； a hollow vial puncturing spike (14) that protrudes into the vial connection port and is in fluid communication with a syringe-adapter-element connection port (16) that extends from the body； and a plurality of resilient tongues (20) spaced around an inner wall of the body. The resilient tongues are located in cut outs formed in the inner wall of the body. The body comprises a rim (18) that extends outwardly from and continuously about the vial connection port.
