Disclosed herein are synthetic peptides and compositions comprising the same for the treatment and/or prophylaxis of a disease or a condition related to dry eye syndrome, psoriasis vulgaris or multiple myeloma. Also disclosed herein are methods of treating and/or preventing a disease or a condition related to dry eye syndrome, psoriasis vulgaris or multiple myeloma, by administering to a subject in need of such treatment a composition containing a therapeutically effective amount of a synthetic peptide of the present disclosure.在此揭示一種用以治療和/或預防乾眼症、牛皮癬或多發性骨髓瘤相關疾病或症狀的合成胜肽,以及包含所述合成胜肽的組合物。再者,本揭示內容亦揭示一種治療和/或預防乾眼症、牛皮癬或多發性骨髓瘤的方法,藉由施用含有一治療有效量之合成胜肽的組合物至需要治療的個體。