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FORMULATION FOR GONADOTROPINS
专利权人:
CADILA HEALTHCARE LIMITED
发明人:
Chintan PATEL,Mukesh MAHAJAN,Sanjay BANDYOPADHYAY,Sanjee Kumar MENDIRATTA,Bhatt CHANDRESH
申请号:
US15030527
公开号:
US20160250295A1
申请日:
2014.10.31
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a stable composition for gonadotropins. It provides a composition useful for stabilization of gonadotropins while preventing aggregation, dissociation, fragmentation and formation of oxidized species variants in solution for injection. Thus, it prevents instability of protein or polypeptide molecules caused due to aggregation or fragmentation or oxidation during or after formulation. Also, it provides a pharmaceutical composition of gonadotropins, which can be therapeutically used for the treatment of various indications either in single-dose form or in multi-dose form.
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