MARIA-JESUS BLANCO-PILLADO,TATIANA NATALI VETMAN,MATTHEW JOSEPH FISHER,STEVEN LEE KUKLISH
申请号：
MX2014015952
公开号：
MX2014015952A
申请日:
2013.06.20
申请国别(地区):
MX
年份:
2015
代理人:
摘要：
The present invention provides a compound of the Formula II: wherein A is: * R 1 is CH3, CF 3, or F； * R 2 is H, CH3, or F； * R 3 is CH3, OCH 3, OH, F； R 4 is OH or CH 20H； and * X is CH or N； These compounds are selective EP4 inhibitors and are useful for the treatment of inflammatory conditions such as arthritis.La presente invención proporciona un compuesto de la Fórmula II: en donde A es: * R 1 es CH3, CF3, o F； * R2 es H, CH3, o F； * R3 es CH3, OCH3, OH, F； R4 es OH o CH20H； y * X es CH o N； o una sal del mismo farmacéuticamente aceptable. Formula II.
