YI GAO,CHARLES W. HUTCHINS,LISSA T. NELSON,MARK A. MATULENKO,RYAN G. KEDDY,TAMMIE K. JINKERSON,MICHAEL D. TUFANO,KATHY SARRIS,KEVIN R. WOLLER,JEAN C. CALIFANO,WENKE LI,CHARLES A FLENTGE,DAVID A DEGOEY
申请号：
PT13191041
公开号：
PT2692346E
申请日:
2011.10.12
申请国别(地区):
PT
年份:
2016
代理人:
摘要：
PROBLEM TO BE SOLVED: To provide a compound that is effective in inhibiting the function of non-structural protein NS5A which is an essential component in the replication of C type hepatitis virus ("HCV").SOLUTION: Provided is a compound exemplified by methyl{(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidine-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-[N-(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazole-5-yl) pyrrolidin-2-yl]-6-fluoro-1H-benzimidazole-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutanoic-2-yl}carbamate or the like, or a pharmaceutically acceptable salt thereof and a derivative thereof.SELECTED DRAWING: None
