Computed tomography devices, systems, and associated methods are disclosed. The device can include a radiation source coupleable to a rotating gantry to emit radiation from an adjustable focal spot toward a volume of interest. The device can also include a dynamic collimator associated with the radiation source and located between the focal spot and the volume of interest. The dynamic collimator can define an aperture that is adjustable to permit radiation to pass through the volume of interest. The focal spot can be adjustable to maximize resolution within the volume of interest.