The present invention provides a method and composition for promoting hair growth in a mammal which comprises a prostaglandin compound having two hetero atoms at the 15 position as an active ingredient thereof.本發明係提供促進哺乳動物毛髮生長之方法及組成物,該組成物包括在15位置處含有兩個雜原子之前列腺素化合物作為其有效成分。