A system (100) for use in determining one or more parameters of a subject, the system comprising: an acoustic unit (110) for irradiation of an area of interest with acoustic marking radiation, said acoustic unit comprising a generator of signal and an acoustic transducer arrangement, said signal generator being configured and operative to generate at least one coding signal in the form of an arbitrary sequence to actuate said acoustic transducer arrangement for generating the acoustic marking radiation comprising the minus an acoustic marking beam which is a continuous acoustic wave coded in the form of a predetermined function of at least one acoustic radiation parameter that varies over time during a predetermined time interval used for measurements, said function having predetermined close self-correlation with respect to a predetermined delay d defined by a system time resolution； an optical unit (101C) configured and operative to irradiate at least a part of the area of interest with at least one electromagnetic beam of a predetermined frequency range, to detect an electromagnetic radiation response of said at least part of the area of interest and generate indicative data thereof, said electromagnetic radiation response marked by the acoustic radiation comprising； and a control unit (120) that is configured and operative to receive and process said generated data indicative of the electromagnetic radiation response at different time delays from the start of the generation of the acoustic wave, said processing comprising cross correlation of said encoded signal and said generated generated data, and the generation of output data indicative of at least one parameter of the subject in the area corresponding to the locations in the medium in which the electromagnetic radiation has been marked by the acoustic radiation.Un sistema (100) para su uso en la determinación de uno o más parámetros de un sujeto, comprendiendo el sistema: una unidad (110) acústica para irra
