IN VITRO PREPARATION METHOD OF ROTAVIRUS DOUBLE-LAYER VIRUS-LIKE PARTICLES

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专利权人:

XIAMEN UNIVERSITY

发明人:

GE, SHENGXIANG,LI, TINGDONG,GUO, QINGSHUN,XU, FEIHAI,ZHANG, JUN,XIA, NINGSHAO

申请号：

EP13838213

公开号：

EP2899267A4

申请日:

2013.06.24

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The invention relates to a method for preparing double-layered virus-like particles of rotavirus in vitro. The method comprises the following steps: purifying rotavirus VP6 proteins from a lysis supernatant, and in vitro assembling double-layered virus-like particles consisting of VP2 proteins and VP6 proteins, wherein the proteins and the virus-like particles can be used for preventing or reducing the clinical symptoms caused by rotavirus infection.

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