A medium- and high-pressure pulsed jet generator (1) for injectingcontrolled volumes of at least one medical liquid (7) includes a high-pressurechamber (2) and at least one connector (24) for at least one flexible pouchcontaining the medical liquid. The flexible pouch/es (6) is/are connected, viaaconnection tube, to a hydraulic sequencer (28) which is mounted in the high-pressurechamber, is exposed to the pressure inside the chamber (2), sequencesthe liquid discharged from the flexible pouch into a pulsed jet (11), iscomposedof a hydraulic connection (20) that is designed as or includes a deformableflexible sleeve (29) hydraulically communicating with the pouch/es (6) at theinletand with a hand-held intervention element (40) or a catheter at the outlet,andincludes hydraulic stops (31, 32) that are disposed on both sides of theflexibledeformable sleeve (29) and are operated using a control element (33).