An agricultural sprayer system includes a solution circuit including solution lines and a fluid pump to pump a solution from the solution tank through the solution lines to the spray nozzles; an air circuit including air lines and a source of compressed air to selectively introduce air pressure into the solution circuit; and a control system including a controller configured to control flow of the solution and the compressed air. The controller is configured to perform a spray cycle in which, during a primary portion, a control valve is controlled to isolate the air circuit from the solution circuit so that the solution is pumped by the fluid pump from the solution tank to the spray nozzles, and in which, during an air pressure application portion, the control valve is controlled so that the solution is forced through the solution circuit by the compressed air.