Cosima Dufour-Schroif,Joachim Wink,Martin Gerlitz,Hélène Olivan,Michael Kurz
申请号:
US13056751
公开号:
US08765799B2
申请日:
2009.07.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to streptospirole derivatives of the general formula (I), wherein R1, R2, R3, X1, X2, Y1 and Y2 are as defined herein, a process for the preparation of said compounds by fermenting the microorganism Streptomyces sp. ST 108140 (DSM 19369) and optionally derivatizing the compounds produced by said microorganism, a pharmaceutical composition comprising at least one compound of the formula (I), and the use of a compound of the formula (I) for the preparation of a medicament for the treatment and/or prophylaxis of bacterial infections.