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Nk cell-activating fusion protein, nk cell, and pharmaceutical composition including same
专利权人:
Korea Research Institute of Bioscience and Biotechnology
发明人:
Kim, Seok Ho,Lee, Jaemin,Cho, Duck
申请号:
AU2018248672
公开号:
AU2018248672A1
申请日:
2018.04.05
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention relates to a fusion protein for treating cancer, and uses thereof. The fusion protein for preventing or treating cancer according to the present invention includes: an antibody or fragment thereof that binds to a tumor-associated antigen; a linker; and a fusion polypeptide including a natural killer cell-inducing protein of CXCL16. Accordingly, when coadministered with a natural killer cell, which is an immunocyte therapeutic agent, the fusion protein greatly increases the introduction of the natural killer cell into a cancer expressing a specific antigen, and thus exhibits a remarkable effect in the prevention or treatment of cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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