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Solid dosage form for the ocular administration of an active principle, a soluble, solid ophthalmic insert and the production method thereof
专利权人:
Saïd El Meski
发明人:
Saïd El Meski,Philippe Tourrette,Jean-Marc Aiache,Marie Di Battista,Gilbert Serpin
申请号:
US10499058
公开号:
US08663678B2
申请日:
2002.12.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A solid dosage form for the ocular administration of an active principle includes at least one biocompatible, water-soluble excipient for ophthalmic use. The form is obtained using a method which is selected from among the following: direct compression, dry compression, wet compression, compression of a lyophilizate, the compression being carried out a temperature below 45° C., or lyophilization, such that the form can disintegrate and release the active principle in the conjunctival sac. The invention also relates to an ophthalmic insert having the aforementioned dosage form which is appropriately dimensioned for ocular administration.
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