Disclosed are an ultrasound diagnosis device and an operating method of the same. The operating method of an ultrasound diagnosis device includes generating a first ultrasound image based on first ultrasound signals received from an object at a first point in time, calculating a value of at least one parameter of the object based on the first ultrasound image, generating a second ultrasound image based on second ultrasound signals received from the object at a second point in time, calculating a value of the at least one parameter of the object based on the second ultrasound image, and displaying a comparative image obtained by comparing the first and second ultrasound images and a comparative result obtained by comparing the calculated values of the at least one parameter.