Process for the preparation of unsubstituted or substituted 2-amino-[1,2,4]triazolopyrimidines which comprises combining A) 2-amino-pyrimidine orits derivatives with alkyloxycarbonyl isothiocyanate or aryloxycarbonylisothiocyanate with B) hydroxyl ammonium salt and a base wherein the reactionis carried out in a polar aprotic organic solvent in the temperature range offrom 40 to 150 ~C.