Douglas J. K. Weaver,Jun Li,Zheng Zhang,Abby N. Deleault,Eric W. Marchese,Phu C. Nguyen,Chad C. Huval,Michael A. Bouchard,Arthur J. Coury,Christopher R. Loose
申请号：
US13156904
公开号：
US08574660B2
申请日:
2011.06.09
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface.
