1, 2, 3-TRIAZOLES 1,5-DISUBSTITUÉS QUI SONT DES INHIBITEURS DES GTPASES RAC/CDC42

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专利权人:

University Of Puerto Rico

发明人:

VLAAR, Cornelis P.,DHARMAWARDHANE FLANAGAN, Suranganie,HERNANDEZ-O'FARRILL, Eliud,CASTILLO-PICHARDO, Linette

申请号：

EP17790459

公开号：

EP3448380A4

申请日:

2017.04.27

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Compounds are disclosed that inhibit RhoGTPases that are useful for inhibiting hyperprofilerative and neoplastic diseases. Specifically, the compounds inhibit the GTPases Rac and Cdc42 that are overactive or overexpressed in signaling pathways in cancer and metastasis. Methods for treatment of cancer and hyperproliferative diseases are disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/