An ultrasound imaging diagnosis apparatus and a method for supporting safe and exact puncturing into a target region in a patient's body are provided. In the apparatus, a regions setting unit sets a target tumor region for puncturing, blood vessel and organ regions that are located near the tumor region based on 3-D volume data. To avoid insertions into blood vessel and organ regions, a needle position detecting unit detects the tip position and inserting direction of the needle before and during insertion. An expected inserting position calculating unit calculates an expected inserting position and an insertion error region to the tumor region based on the tip position data, inserting direction data and needle characteristic data. A puncturing navigation data generating unit generates puncturing navigation data by composing tumor region data, organ region and blood vessel regions data, and data relating to the expected inserting position and insertion error region.
