The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV； modified APMV prepared by such methods； DNA and protein sequences； and methods for infecting cells and host animals with such recombinant APMV. The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV； modified APMV prepared by such methods； DNA and protein sequences； and methods for infecting cells and host animals with such recombinant APMV. Herein disclosed is a method, comprising: forming a dispersion under high shear comprising gas bubbles of an oxidant dispersed in a liquid phase, wherein the bubbles have a mean diameter of less than 1.5 micron； and contacting the dispersion with an oxidation catalyst to produce a product stream, wherein the product stream comprises a substance selected from the group consisting of dicarboxylic acid, benzoic acid, 2- methylbenzoic acid, 3- methylbenzoic acid, 4-methylbenzoic acid, and phthalic anhydride. In some cases, forming the dispersion under high shear comprises introducing the oxidant and the liquid phase into a high shear device comprising at least one rotor and at least one complementarily-shaped stator. Herein also disclosed is a system for producing a substance selected from the group consisting of dicarboxylic acid, benzoic acid, 2- methylbenzoic acid, 3- methylbenzoic acid, 4-methylbenzoic acid, and phthalic anhydride.La presente invención incluye composiciones o vacunas APMV diseñadas. La vacuna o composición puede ser una composición o vacuna APMV recombinante. La presente invención incluye métodos para modificar el genoma de APMV para producir APMV recombinante； A
