Dianna M. Murphy JORDAN,Brian Thomas MARTINSON,Christine Margaret MUEHLENTHALER,Axel NEUBAUER,Arun V. IYER
申请号：
US15846975
公开号：
US20180125957A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to an immunogenic composition comprising: a) one or more antigen of M. hyorhinis and one or more antigens of M. hyosynoviae； and b) a pharmaceutically acceptable carrier. Furthermore, the present invention relates to an immunogenic composition that comprises a) one or more mycoplasma antigens of mycoplasma bacteria selected from the group consisting of M. hyorhinis, M. hyopneumoniae and M. hyosynoviae； and b) one or more components of a eukaryotic cell system. Moreover, the present invention also provides an immunogenic composition obtained by a method comprising a) cultivation of a mycoplasma bacteria selected from the group consisting of M. hyorhinis, M. hyopneumoniae and M. hyosynoviae in a serum-reduced, eukaryotic cell system； b) obtaining an antigen of such mycoplasma bacteria； and c) addition of a pharmaceutically acceptable carrier.
