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polycyclic tlr7 / 8 antagonists and their use in the treatment of immune disorders
专利权人:
MERCK PATENT GMBH
发明人:
BRIAN A. SHERER,NADIA BRUGGER
申请号:
BR112018011556
公开号:
BR112018011556A2
申请日:
2016.12.16
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates to the compounds of formula I and pharmaceutically acceptable compositions thereof, useful as tI7 / 8 antagonists. in formula (i), ring a is aryl or heteroaryl; ring b is aryl or heteroaryl; and x is c (r4) 2, o, nr4, s, s (r4), or s (r4) 2.a presente invenção refere-se aos compostos de fórmula i e composições farmaceuticamente aceitáveis dos mesmos, úteis como antagonistas de tlr7/8. na fórmula (i), o anel a é arila ou heteroarila; o anel b é arila ou heteroarila; e x é c(r4)2, o, nr4, s, s(r4), ou s(r4)2.
来源网站:
中国工程科技知识中心
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