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Methods and compositions for regulating airway tissue remodelling
专利权人:
The University of Sydney
发明人:
Lau, Justine Leeman,Oliver, Brian Gregory George Oliver,Burgess, Janette Kay,Black, Judith Lee
申请号:
AU2008318288
公开号:
AU2008318288B2
申请日:
2008.10.31
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Provided herein are methods and compositions for regulating airway tissue remodellingand for treating or preventing conditions associated with airway inflammationand/or airway tissue remodelling. The methods comprise normalising fibulin-1levels in said tissue relative to normal endogenous levels. In an embodimentthe methods comprise administering to a subject in need thereof an effectiveamount of at least one agent capable of inhibiting the expression and/or activityof fibulin-1.
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