Based on anatomy recognition from three-dimensional live imaging of a volume, one or more portions (204, 208) of the volume are selected in real time. In further real time response, live imaging or the portion(s) is performed with a beam density (156) higher than that used in the volume imaging. The one or more portion may be one or more imaging plane selected for optimal orientation in making an anatomical measurement (424) or display. The recognition can be based on an anatomical model, such as a cardiac mesh model. The model may be pre-encoded with information that can be associated with image locations to provide the basis for portion selection, and for placement of indicia (416, 420, 432, 436) displayable for initiating measurement within an image provided by the live portion imaging. A single TEE or TTE imaging probe (112) may be used throughout. On request, periodically or based on detected motion of the probe with respect to the anatomy, the whole process can be re-executed, starting back from volume acquisition (S508).