DIFFERENTIALLY METHYLATED REGIONS OF REPROGRAMMED INDUCED PLURIPOTENT STEM CELLS, METHOD AND COMPOSITIONS THEREOF

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专利权人:

Andrew P. Feinberg

发明人:

Andrew P. Feinberg,George Q. Daley

申请号：

US13184426

公开号：

US20120164110A1

申请日:

2011.07.15

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Provided herein are differentially methylated regions (DMRs) of reprogrammed iPS cells (R-DMRs) and methods of use thereof. The invention provides methods for detecting and analyzing alterations in the methylation status of DMRs in iPS cells, somatic cells and embryonic stem (ES) cells as well as methods for reprogramming somatic cells to generate an iPS cell.

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中国工程科技知识中心

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