A balloon catheter for an intravascular catheter system includes an outer inflatable balloon and an inner inflatable balloon that is positioned substantially within the outer inflatable balloon. At a nominal working balloon pressure, the outer inflatable balloon has an outer balloon diameter and the inner inflatable balloon has an inner balloon diameter that is greater than the outer balloon diameter at the nominal working balloon pressure. The inner balloon diameter can be at least approximately 5%, 10%, 15%, 20%, 25% or 30% greater than the outer balloon diameter. The inner balloon diameter can be between approximately 29-35 millimeters, and the outer balloon diameter can be between approximately 23-29 millimeters. The inner inflatable balloon can be less compliant than the outer inflatable balloon. The outer balloon compliance can be at least approximately 2%, 5%, 8%, 10%, 15% or 20% greater than the inner balloon compliance.