Process of Preparing mRNA-Loaded Lipid Nanoparticles

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专利权人:

Translate Bio; Inc.

发明人:

Shrirang Karve,Frank DeRosa,Zarna Bhavsar,Michael Heartlein

申请号：

US15809680

公开号：

US20180153822A1

申请日:

2017.11.10

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a solution of pre-formed lipid nanoparticles and mRNA.

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http://www.ckcest.cn/home/