Chad A. Cowan,Leonardo M.R. Ferreira,Torsten B. Meissner,Jack L. Strominger
申请号：
US15524968
公开号：
US20180141992A1
申请日:
2015.11.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are cells and populations of cells comprising a genome in which the B2M gene has been edited to eliminate surface expression of MHC Class I protein in the cells or population of cells, and methods for allogeneic administration of such cells to reduce the likelihood that the cells will trigger a host immune response when the cells are administered to a subject in need of such cells.
