Macdonald, Lynn,Murphy, Andrew J.,Tu, Naxin,Gurer, Cagan,Voronina, Vera,Stevens, Sean
申请号：
AU2018201402
公开号：
AU2018201402A1
申请日:
2018.02.27
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018201402A120180315.pdf#####ABSTRACT The invention provides genetically modified non-human animals that express a humanized MHC protein (humanized MHC a and P polypeptides), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.
