A method of transferring a mixed drug from a drug mixing device in which drug has been mixed to a drug administration device id disclosed. The method comprises the steps of establishing a fluid coupling in an initial configuration between the drug mixing device and the drug administration device to create an assembly comprising the drug mixing device and drug administration device, wherein the drug administration device is located above the drug mixing device. The method includes the step of inverting the assembly to position it in an inverted configuration such that the drug administration device is located below the drug mixing device. The method includes the step of causing a flow of the mixed drug from the drug mixing device to the drug administration device when the assembly is in the inverted configuration. Also described is a drug mixing device comprising a container for holding a mixed drug and an exit transfer member fluidly connected to the container, the exit transfer member for transferring at least some of the mixed drug to a drug administration device. The exit transfer member is arranged such that fluid flow of the mixed drug between the drug mixing device and the drug administration device can occur only when the fluid transfer assembly is placed substantially in a specified orientation.
