Bicyclic compounds, their production and use

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专利权人:

トビラ セラピューティクス インク

发明人:

白石 充,馬場 昌範,合川 勝二,神崎 直之,瀬戸 雅樹,飯澤 祐史

申请号：

JP2009147839

公开号：

JP5275148B2

申请日:

2009.06.22

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R 1 is a 5- to 6-membered ring group which may be substituted； X 1 is a bond or the like； ring A is a 5- to 6-membered ring group which may be substituted； ring B is a 8- to 10-membered ring group which may be substituted； X 2 is a bivalent group of 1 to 4 atoms； Z 1 is a bivalent cyclic ring group or the like； Z 2 is a bond or the like； and R 2 is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/