Mark BLASKOVICH,Matt COOPER,Andrea RANZONI,Wanida PHETSANG,Marwa HASSAN
申请号：
US16467634
公开号：
US20200078466A1
申请日:
2017.12.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A construct comprising: (i) an optionally derivatized glycopeptide antibiotic； (ii) a nanoparticle； and (iii) a first linker connecting (i) and (ii) is provided. The construct may further comprise a second linker located between the first linker and (ii). The nanoparticle may be a separation nanoparticle, such as a magnetic separation nanoparticle. The glycopeptide antibiotic may be selected from the group consisting: of vancomycin； teicoplanin； oritavancin； telavancin； chloroeremomycin； and balhimycin. Also provided are related methods of producing and using the construct, such as methods of separation of bacteria from a sample by binding the bacteria to the construct.
