Methods, apparatus and systems for tissue dissection and testing are disclosed herein. A method for tissue dissection and testing may comprise inserting a tissue dissecting wand (TD) through an incision in a patients body. The TD may comprise a tip having a plurality of protrusions with lysing segments positioned between the protrusions to dissect and/or modify tissue. The TD may also comprise a sensor dock positioned on top of the TD that is configured to allow tissue and/or body fluid contact to a sensor. After separating tissue using the lysing segment(s) to access a target region, the sensor may be activated and moved around within the target region to assess tissues.
