STOLOFF, GREGORY ALAN,CAPARROS-WANDERLEY, WILSON ROMERO
申请号:
NZ58316008
公开号:
NZ583160A
申请日:
2008.09.11
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound comprising: (a) a first component capable of binding to estrogen receptor positive (ER+) cell receptors, wherein the first component is a selective estrogen receptor modulator (SERM) and (b) a second component wherein the second component is a ribosome inactivating toxin and is conjugated to the first component. Also disclosed is the use of the compound in the manufacture of a medicament for the treatment of a cancer comprising ER + cancer cells.