Rohit N. Kulkarni,Abdelfattah El Ouaamari,Daniel Margerie,Matthias Lohmann,Jean Claude Guillemot,Denis Loyaux
申请号:
US14186054
公开号:
US20150366940A1
申请日:
2014.02.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compositions and methods of use are provided for improving β cell function and promoting pancreatic β cell proliferation in vitro, in vivo and ex vivo. The active agents of the pending invention comprise Serpin family peptides (e.g., SerpinB1), functional and structural analogs of Serpin family peptides and nucleic acids encoding Serpin family peptides, as well as active fragments thereof.