Lakshminarayana Narayana;Vidya G. Kattige;Laxmikant A. Gharat;Neelima Khairatkar-Joshi;Nagarajan Muthukaman
发明人:
Laxmikant A. Gharat,Nagarajan Muthukaman,Lakshminarayana Narayana,Neelima Khairatkar-Joshi,Vidya G. Kattige
申请号：
US13283786
公开号：
US20120108583A1
申请日:
2011.10.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.
