PROMÉDICAMENTS DE 4-HYDROXYTAMOXIFÈNE ET D'ENDOXIFÈNE À BASE DE BORE UTILISÉS COMME TRAITEMENT POUR LE CANCER DU SEIN

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专利权人:

XAVIER UNIVERSITY

发明人:

ZHENG, SHILONG,WANG, GUANGDI,JIANG, QUAN,ZHONG, QIU,ZHANG, QIANG

申请号：

EP13758606

公开号：

EP2822955A4

申请日:

2013.03.05

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present disclosure relates to boron-based 4-hydroxytamoxifen and endoxifen prodrugs and the synthesis of the same. Further, the present disclosure teaches the utilization of the boron-based 4-hydroxytamoxifen and endoxifen prodrugs in a treatment for breast cancer. wherein R 1 is KF 3 B, (HO) 2 B, NaF 3 B, wherein the R 1 substituent point of attachment is on the Boron atom； and R 2 is methyl or hydrogen.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/