The invention relates a method for producing a pharmaceutical composition, comprising the steps of: providing a liquid collected from a mammal, which liquid comprises cellular constituents of blood, providing a container having an internal surface, contacting said liquid with said internal surface, incubating said liquid contacted with said internal surface for an incubation time, wherein said liquid is agitated with an agitation means at least once during said incubation time, and after said incubation time has passed, obtaining said pharmaceutical composition by steps comprising (1) collecting said liquid or (2) removing part of or the entirety of said cellular constituents from said liquid and collecting the remainder.