A computer-controlled micro-instrumentation biochemical reaction environment system includes an electrically-controllable microfluidic routing system, at least one microreaction chamber, at least one micro-instrumentation device, and at least one electronic microprocessor. The microreaction chamber supports at least one chemical reaction associated with a biological signaling pathway. The micro-instrumentation device measures at least one physical quantity associated with the signaling pathway. The microprocessor transmits electrical control signals, receives electrical measurement signals, and executes at least one software algorithm. The microreaction chamber is connected to the microfluidic routing system to receive and transmit at least a fluid or gas, and the electronic microprocessor receives electrical measurement signals from the micro-instrumentation device via a first electric interface and transmits electrical control signals to electrically-controllable microfluidic routing system via a second electrical interface. The microfluidic routing system can deliver a drug to the microreaction chamber to influence a chemical reaction associated with a biological signaling pathway.
