Daesoo Kim,Ki Young Chang,Hyeyeon Park,Young Gyun Park
申请号：
US12755851
公开号：
US08319007B2
申请日:
2010.04.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are an α1/CaV3.1 double knockout mouse or α1−/− Emx1-Cre mouse with enhanced essential tremor and a screening method of therapeutic agents for essential tremor by using the same. The α1/CaV3.1 double knockout mouse or α1−/− Emx1-Cre mouse of the present invention may be usefully used for development of therapeutic agents for essential tremor because the mouse exhibits essential tremor strong and evident enough to be visually confirmed, compared to an α1 knockout mouse.
