BAFFERT, FABIENNE,RADIMERSKI, THOMAS,GADBAW, BRIAN
申请号：
MYPI 2013004204
公开号：
MY165097A
申请日:
2012.06.13
申请国别(地区):
MY
年份:
2018
代理人:
摘要：
THE INVENTION RELATES TO A COMBINATION WHICH COMPRISES: (A) COMPOUND A ((R)-3-(4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYLPROPANENITRILE) OF FORMULA (A): OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND (B) COMPOUND B (N-HYDROXY-3-[4-[[[2-(2-METHYL-1H-INDOL-3-YL)-ETHYL]-AMINO]METHYL]PHENYL]-2E-2-PROPENAMIDE) OF FORMULA (B): OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR SIMULTANEOUS, CONCURRENT, SEPARATE OR SEQUENTIAL USE, ESPECIALLY FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES. THE INVENTION ALSO RELATES TO PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH A COMBINATION AND TO A METHOD OF TREATING PROLIFERATIVE DISEASES, IN A MAMMAL, PARTICULARLY A HUMAN, WITH SUCH A COMBINATION. THE PRESENT INVENTION FURTHER ALSO RELATES TO A COMMERCIAL PACKAGE OR PRODUCT COMPRISING SUCH A COMBINATION.
