TRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF

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专利权人:

Japan Tobacco Inc.

发明人:

Hironobu Nagamori,Ikuo Mitani,Masaki Yamashita,Takahiro Hotta,Yuichi Nakagawa,Masatoshi Ueda

申请号：

US14626243

公开号：

US20150266834A1

申请日:

2015.02.19

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Provided is a compound having an mPGES-1 inhibitory activity and useful for the prophylaxis or treatment of pain, rheumatism, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinal disease, systemic scleroderma and cancer including colorectal cancer.A compound represented by the formula [I] or a pharmaceutically acceptable salt thereof:wherein each symbol is as defined in the SPECIFICATION.

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