The present invention relates to a medicament delivery device (100) having a a drive mechanism arranged to drive a plunger rod (12). A last dose limiting mechanism is arranged to interact with the drive mechanism and limit the distal end position of an actuator (3) when the plunger rod (12) has reached a pre-determined position between its distal end position and its proximal end position.本發明有關具有一被配置來驅動柱塞桿(12)之驅動機構的藥物輸送裝置(100)。最後劑量限制機構被配置成與該驅動機構互相作用,且當該柱塞桿(12)已抵達其遠側端位置與其近側端位置間之預定位置時,限制致動器(3)之遠側端位置。1‧‧‧後面外殼2‧‧‧容器夾具3‧‧‧致動器4‧‧‧釋放按鈕5‧‧‧鎖環6‧‧‧鎖定套筒配置8‧‧‧前面外殼100‧‧‧藥物輸送裝置