Nrusingh Prasad MOHAPATRA,Denis K. GUENNET,Bruhaspathy MIRIYALA
申请号:
US16760647
公开号:
US20200325178A1
申请日:
2018.11.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are compositions for the treatment of Gram-positive bacteria infection and inhibition of Gram-positive bacteria growth. The compositions comprise a peptide nucleic acid linked to a cell-penetrating peptide (PNA-CPP). The PNA-CPP conjugate and compositions inhibit expression of bacterial proteins and are optionally administered in the form of nanoparticle compositions and antimicrobial fabrics.