Bradwell, Arthur Randell,Goehl, Hermann,Storr, Markus
申请号:
AU2006236013
公开号:
AU2006236013B2
申请日:
2006.11.15
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2006236013B220121206.pdf#####32 Abstract There is provided a method of reducing blood free light chain concentration in a subject, the method comprising the step of subjecting the subject's blood to haemodialysis, haemodiafiltration or haemofiltration. There is also provided the use of a dialysis membrane which is a membrane that allows passage of molecules having a molecular weight of up to 45kDa in presence of whole blood, and has a molecular weight exclusion limit in water of about 200kDa in the preparation of a haemodialysis unit for conducting haemodialysis, haemodiafiltration or haemofiltration on a subject to reduce blood free light chain concentration in the patient.Figure 1 Blood Lymphl IaukamI j Bone marrow Activated or memory Chroic lmpoc~r B cell ( u) J m!f (CLLJ _Ilcua cnr cell Periphery B cell cfl Germinal odgkin's lymphoma centre B cell ) [gp.,eingm cell Wiesr~ Bone marrow Intact Ught chan Nonsecretory AL amyloldosis] lmniunoglobulln mysloma9 myelomna mysloma