Luigi Vitagliano,Laura Zaccaro,Giancarlo Morelli,Enzo Martegani
申请号:
US11922043
公开号:
US08461110B2
申请日:
2006.06.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Peptides having a structure characterized by the presence of two loops constrained in cyclic structure by the presence of covalent bonds between amino acid side chains, the amino acid sequences of the first and the second loop being substantially homologues to that of loop 1 (residues 29-38) and of loop 4 (residues 92-97) of NGF, respectively, displaying nerve growth factor (NGF) agonist or partial agonist activity.