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Recombinant Measles Virus Useful as a Bivalent Vaccine Against Measles and Malarial Infections
专利权人:
Misako Yoneda;Chieko Kai
发明人:
Chieko Kai,Misako Yoneda
申请号:
US13511082
公开号:
US20120321661A1
申请日:
2009.11.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided herein is a vaccine which is safe and effective against malarial infection and a vector which is used in the manufacture of this vaccine and to provide a bivalent vaccine which exhibits an excellent preventive effect against measles virus and malarial infection and which eliminates complexity at the time of inoculation. Also provided is a recombinant measles virus in which is inserted a gene which encodes a protein involved in preventing malarial infection in the measles virus genome. The present invention also provides a bivalent vaccine against measles and malarial infection which contains the recombinant measles virus. It also provides a method of manufacturing a vaccine against malarial infection which is characterized by using a measles virus as a vaccine vector in the manufacture of a vaccine against malarial infection
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