The Ohio State University Research Foundation;Board of Regents of the University of Texas System
发明人:
Mauro Ferrari,Ennio Tasciotti,Jason Sakamoto
申请号：
US14725570
公开号：
US10143658B2
申请日:
2015.05.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Multistage delivery vehicles are disclosed which include a first stage particle and a second stage particle. The first stage particle is a micro or nanoparticle that contains the second stage particle. The second stage particle includes an active agent, such as a therapeutic agent or an imaging agent. The multistage delivery vehicle allows sequential overcoming or bypassing of biological barriers. The multistage delivery vehicle is administered as a part of a composition that includes a plurality of the vehicles. Methods of making the multistage delivery vehicles are also provided.
