A method for making a surgical guide for bone harvesting identifying in a three-dimensional image of a bone one or more sensitive anatomic structures and a volume of bone suitable for being removed. The volume is delimited by a portion of an outer surface of the bone defining a perimeter and by a mantle extending from the perimeter inside of the bone. The method also includes designing the surgical guide which includes defining a guide surface including a work area delimited by guide walls. The method also includes angling at least one of the guide walls so that the guide wall includes a face that constitutes a geometrical extension of a portion of the mantle when the guide is rested on the outer surface of the bone such that the face includes at least one segment forming a predetermined angle with respect to the guide surface.