Vinayak Sant;Dorothee Le Garrec;Damon Smith;Francois Ravenelle;Miloud Rahmouni;David Lessard;Sandra Gori
发明人:
Francois Ravenelle,Dorothee Le Garrec,David Lessard,Sandra Gori,Damon Smith,Miloud Rahmouni,Vinayak Sant
申请号：
US13643038
公开号：
US20130039864A1
申请日:
2011.04.21
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The disclosure relates to a non-intravenous dosage for administration of a liquid biologically active agent. The dosage form contains a solid formulation of the liquid biologically active agent, e.g. propofol, in intimate association with at least one stabilizing agent, e.g. an amphiphilic polymer or surfactant. A liquid biologically active agent is converted to a solid product, e.g. a powder, that can be easily incorporated into a number of different non-intravenous dosage forms. Upon hydration, a nanodispersion or micelle loaded with the active agent is formed. The dosage form can provide a non-intravenous route of administration for active agents that are typically only administered intravenously. Methods, uses, kits and commercial packages related to the non-intravenous dosage form are also disclosed.
